|
|
glycine + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> S-aminomethyldihydrolipoylprotein + CO2
|
1.4.4.2
glycine dehydrogenase (aminomethyl-transferring)
|
–
|
K
|
| |
BRENDA:
BR36885;
BS259167
KEGG:
R03425
SABIO-RK:
3223
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + NAD+ <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + NADH + H+
|
1.8.1.4
dihydrolipoyl dehydrogenase
|
–
|
MK
|
| |
BRENDA:
BR36970
KEGG:
R03815;
R07618;
R08550
MetaCyc:
1.8.1.4-RXN;
RXN-7716
SABIO-RK:
9140
|
|
|
|
protein + lipoic_acid + ATP <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + AMP + diphosphate + H+
|
6.3.1.20
lipoate---protein ligase
|
–
|
K
|
| |
BRENDA:
BR48679;
BS398781
KEGG:
R11143
MetaCyc:
RXN-17127
|
|
|
|
lipoyl-AMP + protein <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + AMP + H+
|
6.3.1.20
lipoate---protein ligase
|
–
|
M
|
| |
BRENDA:
BR51616
KEGG:
R07771
MetaCyc:
RXN-8655
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + ROOH <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + H2O + an_alcohol
|
1.11.1.28
lipoyl-dependent peroxiredoxin
|
–
|
|
| |
KEGG:
R12602
MetaCyc:
RXN-20690
|
|
|
|
Lipoyl-[acp] + protein <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + [acyl-carrier_protein]
|
2.3.1.181
lipoyl(octanoyl) transferase
|
–
|
|
| |
KEGG:
R07769
|
|
|
|
[dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + H2O <=> protein + lipoic_acid
|
3.5.1
|
–
|
M
|
| |
MetaCyc:
RXN-13031
|
|
|
|
[glycine-cleavage_complex_H_protein]_N6-[(R)-lipoyl]-L-lysine + protein <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + [glycine_cleavage_system_lipoyl-carrier_protein]-L-lysine
|
2.3.1.200
lipoyl amidotransferase
|
–
|
M
|
| |
MetaCyc:
RXN-13032
|
|
|
|
enzyme_N6-(dihydrolipoyl)lysine + [2-Cys_peroxiredoxin]_with_a_disulfide_bond <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + [2-Cys_peroxiredoxin]_with_reduced_L-cysteine_residues
|
not assigned
|
–
|
|
| |
MetaCyc:
RXN-20689
|
|
|
|
pyruvate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_acetyltransferase]_S-acetyldihydrolipoyllysine + CO2
|
1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
|
–
|
|
| |
BRENDA:
BR33749
|
|
|
|
pyruvate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> acetylated_lipoyl_domain + CO2
|
1.2.4.1
pyruvate dehydrogenase (acetyl-transferring)
|
–
|
|
| |
BRENDA:
BS451471
|
|
|
|
2-oxobutyrate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(propanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BS231867
|
|
|
|
2-oxoglutarate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_succinyltransferase]_S-succinyldihydrolipoyllysine + CO2
|
1.2.4.2
oxoglutarate dehydrogenase (succinyl-transferring)
|
–
|
|
| |
BRENDA:
BR33750
|
|
|
|
4-methyl-2-oxopentanoate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(3-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BS371974
|
|
|
|
4-methyl-2-oxopentanoate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BS413189
|
|
|
|
2-oxoisovalerate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylpropanoyl)dihydrolipoyllysine + CO2 + 2 H+
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BR33751
|
|
|
|
2-oxoisovalerate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-butanoyl-dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BS371738
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + reduced_[4Fe-4S]_cluster <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + oxidized_[4Fe-4S]_cluster
|
2.8.1.8
lipoyl synthase
|
–
|
|
| |
BRENDA:
BS436549
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur + S-adenosyl-L-methionine <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + 2 L-methionine + 2 5''-deoxyadenosyl_radicals
|
2.8.1.8
lipoyl synthase
|
–
|
B
|
| |
BRENDA:
BS380225
|
|
|
|
protein_N6-(octanoyl)lysine + sulfur-(sulfur_carrier) + S-adenosyl-L-methionine + [2Fe-2S]-center <=> [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine + (sulfur_carrier) + L-methionine + 5''-deoxyadenosine + [2Fe-2S]-center
|
2.8.1.8
lipoyl synthase
|
–
|
|
| |
BRENDA:
BS436548
|
|
|
|
3-methyl-2-oxopentanoate + [dihydrolipoyllysine-residue(2-methylpropanoyl)transferase]-lipoyllysine <=> [dihydrolipoyllysine-residue_(2-methylpropanoyl)transferase]_S-(2-methylbutanoyl)dihydrolipoyllysine + CO2
|
1.2.4.4
3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
|
–
|
|
| |
BRENDA:
BS231866
|
|
